Current Trials

ACTIVELY ENROLLING STUDIES

ONCOLOGY

BREAST
SHAVE2: A Multicenter Randomized Controlled Trial of Routine Shave Margins vs. Standard Partial Mastectomy in Breast Cancer Patients.

A011401- (BWEL): Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer.

A011502 - (ABC-ASPIRIN): A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node-Positive HER2 Negative Breast Cancer (ABC Trial).
   
LEUKEMIA
inform CLL: A Disease Registry for Patients with Chronic Lymphocytic Leukemia.
 
LUNG
ALCHEMIST Trials:
  • A151216 (ALCHEMIST-Screen) Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial.
  • EA5142 (ALCHEMIST-ANVIL) Adjuvant Nivolumab in Resected Lung Cancers.
  • A081105 (ALCHEMIST-EGFR) Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant NSCLC.
  • E4512 (ALCHEMIST-ALK) Phase III Double-blind Trial for Surgically Resected Early Stage NSCLC: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK ) Fusion Protein.

MDS/AML
Connect MDS/AML: The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry.

MOLECULAR SCREENING FOR SOLID TUMORS
EAY 131 (MATCH): Molecular Analysis for Therapy Choice (MATCH).
 
MULTIPLE MYELOMA
Multiple Myeloma Patient Registry: Multiple Myeloma Patient Registry.

PANCREAS
S1505: A Randomized Phase II Study of Perioperative mFOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma.
 
RENAL
EA8143 (PROSPER): A Phase 3 Randomized Study Comparing Perioperative Nivolumab vs. Observation in Patients with Localized Renal Cell Carcinoma Undergoing Nephrectomy.
 

CARDIOLOGY

Left Atrial Appendage Occluder (Atrial Fibrillation)
AMULET: AMPLATZER Amulet LAA Occluder Randomized Controlled Trial.
ASAP- TOO: Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation.

Congestive Heart Failure
PIONEER HF: In-hospital initiation of sacubitril/valsartan vs. enalapril to assess changes in NO-proBNP through 8 weeks of treatment following an episode of acute decompensated heart failure.

TAVI (Atrial Fibrillation)
ENVISAGE (TAVI): Transcatheter Aortic Valve Implantation (TAVI) in Patients with Atrial Fibrillation.

CRT-Ds
SMART- CRT: Strategic Management to Optimize Response to Cardiac Resynchronization Therapy.

For More Information: 
If you would like additional information about the Center for Research, please send your name, company or practice name, address and telephone number to the following address:
 
Watson Clinic Center for Research
1600 Lakeland Hills Blvd
Lakeland, FL 33805
Attn: Noreen McGowan, BSN, CCRC, Director
Phone 863-688-6826 · FAX 863-688-5842
 
Please indicate which of the following type(s) of information you would like:
  • Additional information about current protocols
  • Center for Research grants
  • Contributing to Center for Research funding
  • Involvement in Center for Research protocols

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